上海儒百生物(Schbio Biotech)
专业血液免疫学产品生产商

Product Description
Human CD160 Protein, hFc Tag
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Brand : RecProtein®
Synonym : CD160,BY55,NK1,NK28
Molecule : CD160
Catalog : B1579
Qty : 1mg, 5mg
18521561575  需求咨询
Datasheet

Source

Human CD160, hFc Tag   is expressed from human 293 cells (HEK293). It contains AA Ile 27 - Ser 159 (Accession # AAH14465).

Predicted N-terminus: Ile 27


Endotoxin

Less than 0.01 EU/mg by the LAL method.


Purity

>95% as determined by SDS-PAGE.


Bioactivity

ELISA

BIACORE (With our Research Grade Biosimilar Antibody products);


Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.


Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.


Storage

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

No activity loss was observed after storage at:

4-8°C for 12 months in lyophilized state;

-70°C for 3 months under sterile conditions after reconstitution.


Background

CD160 antigen is also known as natural killer cell receptor BY55, is a 27 kDa glycoprotein, contains 1 Ig-like V-type (immunoglobulin-like) domain. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis.


Reference

(1) Anumanthan A., et al., 1998, J. Immunol. 161:2780-2790.

(2) Agrawal S., et al., 1999, J. Immunol. 162:1223-1226.



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