Schbio Biotech

Product Description
Cord Blood CD34+ Cells
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Brand : StemExpress®
Molecule : 脐血
Price : Require
Datasheet

Product Description

CD34 is a glycosylated transmembrane protein and represents a well established marker for human hematopoietic stem and progenitor cells in peripheral blood, bone marrow, cord blood, and fetal liver. CD34+ cells are selfrenewing, multipotent stem cells that give rise to all blood cells of the immune system through a process called hematopoiesis. As hematopoietic stem cells progress through hematopoiesis they generate the myeloid (monocytes, macrophages, granulocytes, megakaryocytes, dendritic cells, erythrocytes), and lymphoid (T cells, B cells, NK cells) lineages. The highly specialized cells that arise from hematopoietic stem cells work collaboratively in defending the body against infection and disease.

Schbio offers CD34+ hematopoietic stem and progenitor cells from human cord blood in an assortment of pre selected volumes and formats (fresh or cryopreserved) from single or pooled donors. CD34+ cells are positively selected using immunomagnetic anti CD34 (clone QBEND10) microbeads from cord blood mononuclear cells. Isolated cells are characterized by flow cytometry to ensure a highly pure and viable cell population.

Schbio offers single and mixed donor CD34+ hematopoietic stem and progenitor cells. Mixed donor pools are from two or more donors and are available in larger lots. Single donor cells are isolated from a single umbilical cord blood sample.

Cord blood is collected from mothers that are negative for HIV, HepB, and HepC during pregnancy. Infectious disease testing, LCMV testing and HLA typing on the cord blood can be provided as a custom order.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.


Format
Mixed Donor Catalog #
Single Donor Catalog #
QTY/Unit
Cryo

CBP3400.5C

CBP3401C

CBP3402C

N/A

CBP3405C

CB3400.5C

CB3401C

CB3402C

CB3402.5C

N/A
0.5 million/vial
1 million/vial
2 million/vial
2.5 million/vial
5 million/vial


Product Specification

Species:
Human
Cell Source:
Umbilical Cord Blood
Product Type:
Primary Cells
Cell Type:
Stem/Progenitor Cells
Donor Attributes:
Maternal Blood HIV-, HepB-, HepC-
Single or Mixed Donor:
Single and Mixed
Purity:
≥90% by Flow Cytometry
Viability:
≥85% by Flow CytometryNote: For cryopreserved samples the freeze thaw cycle may decrease cell viability by 10-15% post thaw.
Contains:
Fresh: StemSpan™Frozen: StemSpan and 10% DMSO


Publications

1.
Halkias et al. (2015) Conserved and Divergent Aspects of Human T-cell Development and Migration in Humanized Mice. Immunol Cell Biol 1-11. doi:10.1038/icb.2015.38.
2.
Cleyrat et al. (2017) Gene Editing Rescue of a Novel MPL Mutant Associated with CongenitalAmegakaryocytic Thrombocytopenia. Blood Advances 1: 1815-1826. doi.org/10.1182/bloodadvances.201600291.




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