Product Description
Mononuclear cells (MNCs) are separated from umbilical cord blood by means of a density gradient centrifugation protocol. The mononuclear cells are composed of lymphocytes (T cells, B cells, and NK cells), monocytes, dendritic cells, and stem/progenitor cells. These cells are critical components of the immune system and play key roles in the humoral and cell mediated immune responses. Mononuclear cells are commonly used in research and clinical applications in the areas of immunology, infectious disease, hematological malignancies, vaccine development, transplant therapy, and high-throughput screening.
StemExpress offers highly pure and viable mononuclear cells from cord blood in an assortment of pre-selected volumes and formats (cryopreserved or fresh). This highly pure population of cells makes them ideal for further isolations of specific cell types within the mononuclear fraction.
Cord blood is collected from mothers that are negative for HIV, HepB, and HepC during pregnancy. Testing on cord blood can be provided as a custom order.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
Format | Catalog # | QTY/Unit |
Cryopreserved | CBMNC150C CBMNC200C CBMNC300C CBMNC015C CBMNC025C | 150 million/vial 200 million/vial 300 million/vial 15 million/vial 50 million/vial |
Product Specification
Species: | Human |
Cell Source: | Umbilical Cord Blood |
Product Type: | Primary Cells |
Cell Types: | Mononuclear Cells, Monocytes, Lymphocytes, Stem/Progenitor Cells, Dendritic Cells |
Donor Attributes: | Maternal Blood HIV-, HepB-, HepC- |
Single or Mixed Donor: | Single |
Viability: | ≥85% by Flow CytometryNote: For cryopreserved samples the freeze thaw cycle may decrease cell viability by 10-15% post thaw. |
Contains: | Fresh: PBS with 5% FBS and 0.5% BSA Frozen: CryoStor™ CS10 (10% DMSO) |