纯度

> 95 % as determined by SDS-PAGE

内毒素

< 0.01 EU per μg of the protein asdetermined by the LAL method

蛋白构建

A DNA sequence encoding the mature form of mouse KIM1 extracellular domain was fused with Fc region of human IgG1 at the N-terminus.

表达宿主

HEK293 Cells

种属

Mouse

缓冲液

Lyophilized from sterile 50mM Tris, 100mMNaCl, pH 8.0
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added asprotectants before lyophilization. Specific concentrations are included in thehardcopy of COA.

运输方式

In general, recombinant proteins areprovided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They areshipped out with blue ice unless customers require otherwise.

稳定性 & 储存条件

Samples are stable for up to twelve monthsfrom date of receipt at -70℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that theprotein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

复溶

A hardcopy of COA with reconstitutioninstruction is sent along with the products. Please refer to it for detailedinformation.

TIM-1 / KIM-1 Protein, Human, Recombinant:Alternative Names

CD365 Protein, Human; HACVR Protein, Human;HAVCR Protein, Human; HAVCR-1 Protein, Human; KIM-1 Protein, Human; KIM1Protein, Human; TIM Protein, Human; TIM-1 Protein, Human; TIM1 Protein, Human;TIMD-1 Protein, Human; TIMD1 Protein, Human

TIM-1 / KIM-1 Background Information

HAV cellular receptor 1 (HAVCR1), alsoknown as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1(TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widelyexpressed with highest levels in kidney and testis. It has been shown to play amajor role as a human susceptibility gene for asthma, allergy and autoimmunity.IgA1lambda is a specific ligand of KIM-1 protein and that their association hasa synergistic effect in virus-receptor interactions. KIM-1 involves in thepathogenesis of acute kidney injury. It had been confirmed that KIM-1 is ahuman urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novelregulatory molecule of flow-induced calcium signaling.

Full Name

hepatitis A virus cellular receptor 1