Schbio Biotech

Therapeutic Antibody Database

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Explore the Structures of Therapeutic Antibodies Deposited in the PDB

The following table maps antibody therapeutics to their Protein Data Bank (PDB) structures. These therapeutics have all advanced to at least Phase II of clinical trials. Some have been withdrawn from the market, or had their clinical trials terminated. Please let us know if we have missed any post-Phase I therapeutic structures by sending an email to opig @ stats.ox.ac.uk.


This page was last updated on 24th July, 2018.



Antibody Therapeutic
Links to Annotated Structures (Bound/Unbound, Resolution)
Abituzumab
4o02 (Bound Fab, 3.61)
Adalimumab
4nyl (Unbound Fab, 2.80)
3wd5 (Bound Fab, 3.10)
Aducanumab
6cnr (Unbound Fab, 2.09)
6co3 (Bound Fab, 2.38)
Alemtuzumab
1bey (Unbound Fab, 3.25)
1ce1 (Bound Fab, 1.90)
Amatuximab
4f33 (Unbound Fab, 1.75)
4f3f (Bound Fab, 2.65)
Andecaliximab
5th9 (Bound Fab, 3.00)
Anifrolumab
4qxg (Unbound Fab, 2.30)
Atezolizumab
5xxy (Bound Fab, 2.90)
5x8l (Bound Fab, 3.10)
Avelumab
5grj (Bound Fab, 3.21)
Bapineuzumab
4ojf (Bound Fab, 2.00)
4onf (Bound Fab, 2.00)
4ong (Bound Fab, 2.20)
4hix (Bound Fab, 2.20)
Basiliximab
1mim (Unbound Fab, 2.60)
3iu3 (Bound Fab, 2.90)
Belimumab
5y9j (Bound Fab, 2.05)
6fxn (Bound Fab, 2.90)
Bezlotoxumab
4np4 (Bound Fab, 2.89)
Bimagrumab
5nhw (Unbound Fab, 1.78)
Briakinumab
5n2k (Unbound Fab, 2.22)
Canakinumab
4g5z (Unbound Fab, 1.83)
5bvj (Unbound Fab, 2.00)
4g6j (Bound Fab, 2.03)
5bvp (Bound Fab, 2.20)
Carlumab
4dn3 (Unbound Fab, 2.60)
4dn4 (Bound Fab, 2.80)
Certolizumab
5wuv (Unbound Fab, 1.95)
5wux (Bound Fab, 2.90)
Cetuximab
1yy8 (Unbound Fab, 2.00)
5th2 (Bound Fab, 1.84)
4gw5 (Bound Fab, 2.20)
4gw1 (Bound Fab, 2.24)
5f88 (Bound Fab, 2.48)
5hyq (Bound Fab, 2.48)
5id0 (Bound Fab, 2.48)
5ir1 (Bound Fab, 2.48)
5ivz (Bound Fab, 2.48)
5iv2 (Bound Fab, 2.48)
5t1k (Bound Fab, 2.48)
5t1l (Bound Fab, 2.48)
5id1 (Bound Fab, 2.49)
5euk (Bound Fab, 2.50)
5ff6 (Bound Fab, 2.50)
5icy (Bound Fab, 2.50)
5iop (Bound Fab, 2.50)
5itf (Bound Fab, 2.51)
5etu (Bound Fab, 2.53)
5t1m (Bound Fab, 2.53)
5esq (Bound Fab, 2.55)
5icz (Bound Fab, 2.55)
5i2i (Bound Fab, 2.55)
5icx (Bound Fab, 2.60)
1yy9 (Bound Fab, 2.61)
5hpm (Bound Fab, 2.67)
4krp (Bound Fab, 2.82)
4kro (Bound Fab, 3.05)
Coltuximab
6ani (Bound Fab, 2.40)
Crenezumab
5kmv (Unbound Fab, 2.50)
5vzy (Bound Fab, 2.32)
Daclizumab
3nfs (Unbound Fab, 2.60)
3nfp (Bound Fab, 2.86)
Drozitumab
4od2 (Bound Fab, 3.20)
Durvalumab
5xj4 (Bound scFv, 2.30)
5x8m (Bound Fab, 2.67)
Eculizumab
5i5k (Bound Fab, 4.20)
Efalizumab
3eo9 (Unbound Fab, 1.80)
3eoa (Bound Fab, 2.80)
3eob (Bound Fab, 3.60)
Epratuzumab
5vkk (Unbound Fab, 2.01)
Etaracizumab
6avq (Bound Fab, 35 - ELECTRON MICROSCOPY)
6avr (Bound Fab, 35 - ELECTRON MICROSCOPY)
6avu (Bound Fab, 35 - ELECTRON MICROSCOPY)
Fresolimumab
3eo0 (Unbound Fab, 1.75)
3eo1 (Bound Fab, 3.10)
Gantenerumab
5csz (Bound Fab, 1.80)
Gevokizumab
4g6k (Unbound Fab, 1.90)
4g6m (Bound Fab, 1.81)
Guselkumab
4m6m (Unbound Fab, 2.00)
4m6n (Unbound Fab, 2.00)
Ibalizumab
3o2d (Bound Fab, 2.19)
Idarucizumab
4jn2 (Unbound Fab, 1.71)
4jn1 (Unbound Fab, 1.89)
Infliximab
5vh3 (Unbound Fab, 2.00)
5vh4 (Unbound Fab, 2.00)
4g3y (Bound Fab, 2.60)
Ipilimumab
5tru (Bound Fab, 3.00)
Isatuximab
4cmh (Bound Fab, 1.53)
Lampalizumab
4d9q (Bound Fab, 2.28)
Lanadelumab
4pub (Unbound Fab, 1.75)
4ogy (Bound Fab, 2.10)
4ogx (Bound Fab, 2.40)
Lebrikizumab
4i77 (Bound Fab, 1.90)
Matuzumab
3c08 (Unbound Fab, 2.15)
3c09 (Bound Fab, 3.20)
Motavizumab
3qwo (Bound Fab, 1.90)
4jlr (Bound Fab, 2.71)
3ixt (Bound Fab, 2.75)
4zyp (Bound Fab, 5.50)
Muromonab
1sy6 (Bound Fab, 2.10)
Natalizumab
4irz (Bound Fab, 2.84)
Necitumumab
3b2u (Bound Fab, 2.54)
3b2v (Bound Fab, 3.30)
Nimotuzumab
3gkw (Unbound Fab, 2.50)
Nivolumab
5ggq (Unbound Fab, 1.90)
Obinutuzumab
3pp3 (Unbound Fab, 2.51)
3pp4 (Bound Fab, 1.60)
Ofatumumab
3giz (Unbound Fab, 2.20)
Olokizumab
4cni (Bound Fab, 2.20)
Omalizumab
4x7s (Unbound Fab, 1.90)
2xa8 (Unbound Fab, 2.41)
4x7t (Unbound Fab, 3.00)
5hys (Bound Fab, 2.50)
5g64 (Bound Fab, 3.72)
Onartuzumab
4k3j (Bound Fab, 2.80)
Opicinumab
4oqt (Bound Fab, 3.23)
Palivizumab
2hwz (Unbound Fab, 1.80)
Panitumumab
5sx5 (Bound Fab, 2.50)
5sx4 (Bound Fab, 2.80)
Pembrolizumab
5dk3 (Unbound Fc, 2.28)
5ggs (Bound Fab, 2.00)
5b8c (Bound Fv, 2.15)
5jxe (Bound Fab, 2.90)
Pertuzumab
4lly (Unbound Fab, 1.60)
4llw (Unbound Fab, 1.95)
4llu (Unbound Fab, 2.16)
1s78 (Bound Fab, 3.25)
Pinatuzumab
6and (Bound Fab, 1.75)
Ponezumab
3u0t (Bound Fab, 2.50)
Ramucirumab
3s34 (Unbound Fab, 2.20)
3s36 (Bound Fab, 3.20)
Ranibizumab
1cz8 (Bound Fab, 2.40)
Rituximab
4kaq (Unbound Fab, 2.48)
2osl (Bound Fab, 2.60)
Rontalizumab
4z5r (Bound Fab, 3.00)
Sifalimumab
4ypg (Bound Fab, 3.00)
Solanezumab
4xxd (Bound Fab, 2.41)
Suvratoxumab
4u6v (Bound Fab, 2.56)
Tanezumab
4edw (Bound Fab, 2.48)
Tezepelumab
5j13 (Bound Fab, 2.30)
Tralokinumab
5l6y (Bound Fab, 1.99)
Trastuzumab
4ioi (Bound Fab, 1.95)
4hjg (Bound Fab, 2.00)
4hkz (Bound Fab, 2.08)
Tremelimumab
5ggv (Bound Fab, 2.00)
Ustekinumab
3hmw (Unbound Fab, 3.00)
3hmx (Bound Fab, 3.00)



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