Schbio Biotech

Whole Bone Marrow

1. Lakatos et al. (2015) Mesenchymal Stem Cells Respond to Hypoxia by Increasing Diacylglycerols. J Cell Biochem 2: 300-307.
2. Beegle et al. (2015) Hypoxic Preconditioning of Mesenchymal Stromal Cells Induces Metabolic Changes, Enhances Survival, and Promotes Cell Retention In Vivo. Stem Cells 33(6): 1818-1828.
3. Adair et al. (2016) Semi-Automated Closed System Manufacturing of Lentivirus Gene-Modified Hematopoietic Stem Cells for Gene Therapy. Nat Commun 7: 13173.
4. Kalomoiris et al. (2016) Fibroblast Growth Factor 2 Regulates High Mobility Group A2 Expression in Human Bone Marrow-Derived Mesenchymal Stem Cells. Cell Biochem 117(9): 2128-2137.
5. Karuna et al. (2018) Identification of a WNT5A-Responsive Degradation Domain in the Kinesin Superfamily Protein KIF26B. Genes 9(4): 196.
6. Adair et al. (2018) Novel Lineage Depletion Preserves Autologous Blood Stem Cells for Gene Therapy of Fanconi Anemia Complementation Group A.Haematol Doi:10.3324/haematol.2018.194571.
7. Awan et al. (2018) FGF2 Induces Migration of Human Bone Marrow Stromal Cells by Increasing Core Fucosylations on N-Glycans of Integrins.Stem Cell Reports S2213-6711(18)30270-30274.
8. Matsui et al. (2018) Dual Role of a C-Terminally Truncated Isoform of Large Tumor Suppressor Kinase 1 in the Regulation of Hippo Signaling and Tissue Growth. DNA and Cell Biology. Online publication at

Whole Peripheral Blood

1. Kozbial et al. (2018) Automated Generation of Immature Dendritic Cells in a Single-Use System. J Immunol Methods 6(457): 53-65.
2. Kozbial et al. (2018) Scale-Up of a Perfusion-Based Dendritic Cell Generation Process. Cell Gene Therapy Insights 4(11): 1117-1130.
3. Blauwkamp et al. (2019) Analytical and Clinical Validation of a Microbial Cell-Free DNA Sequencing Test for Infectious Disease. Nat Microbiol Doi: 10.1038/s41564-018-0349-6.

Whole Maternal Blood 1. Samango-Sprouse et al. (2013) SNP-Based Non-Invasive Prenatal Testing Detects Sex Chromosome Aneuploidies with High Accuracy. Prenat Diagn 33(7): 643-649.
2. Ravi et al. (2018) Validation of a SNP-Based Non-Invasive Prenatal Test to Detect the Fetal 22q11.2 Deletion in Maternal Plasma Samples. PloS One 13(2): e0193476.

Mononuclear Cells

1. Yamada et al. (2014) G0S2 Inhibits the Proliferation of K562 Cells by Interacting with Nucleolin in the Cytosol. Leuk Res 38:     210-217.
2. Yang et al. (2016) Human Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Proliferation of PHA-Activated Lymphocytes In Vitro by Inducing CD4+CD25highCD45RA+ Regulatory T Cell Production and Modulating Cytokine Secretion. Cell Immunol 302: 26-31.
3. Ishikawa et al. (2017) A Novel LSD1 Inhibitor T-3775440 Disrupts GFI1B-Containing Complex Leading to Transdifferentiation and Impaired Growth of AML Cells. Mol Cancer Ther 16: 273-284.
4. Towobola et al. (2017) Novel Immunodeficient Rat Models Offers a Unique Platform for Drug Efficacy Studies in Human Tumor Xenografts. AACR-EORTC-NCI 2017 Annual Meeting Poster.
5. Towobola et al. (2017) Novel Immunodeficient Rat Models Capable of Supporting the Growth of Human Tumor Xenografts. AACR 2017 Annual Meeting Poster.
6. Noto et al. (2018) The SRG™ Rat: A Novel SCID Rat for Humanization Studies. AACR 2018 Annual Meeting Poster.

CD34+ Stem Cells

1. Hudak et al. (2014) Glycocalyx Engineering Reveals a Siglec-Based Mechanism for NK Cell Immunoevasion. Nat Chem Biol 10(1): 69-75.
2. Halkias et al. (2015) Conserved and Divergent Aspects of Human T-Cell Development and Migration in Humanized Mice. Immunol Cell Biol 93(8): 1-11.
3. Cleyrat et al. (2017) Gene Editing Rescue of a Novel MPL Mutant Associated with Congenital Amegakaryocytic Thrombocytopenia. Blood Advances 1: 1815-1826.
4. Eksioglu et al. (2017) Novel Therapeutic Approach to Improve Hematopoiesis in Low Risk MDS by Targeting MDSCs with the Fc-Engineered CD33 Antibody BI 836858. Leukemia 31(10): 2172-2180.
5. Modarai et al. (2018) Efficient Delivery and Nuclear Uptake is Not Sufficient to Detect Gene Editing in CD34+ Cells Directed by a Ribonucleoprotein Complex. Mol Ther Nucl Acids 11: 116-129.
6. Takahashi et al. (2018) Enhanced Antibody Responses in a Novel NOG Transgenic Mouse with Restored Lymph Node Organogenesis. Front Immunol Doi:10.3389/fimmu.2017.02017
7. Cheng et al. (2019) S100A9-Induced Overexpression of PD-1/PD-L1 Contributes to Ineffective Hematopoiesis in Myelodysplastic Syndromes. Leukemia Doi:10.1038/s41375-019-0397-9.

Mesenchymal Stem Cells (MSCs)

1. Dorcemus and Haus (2018) Growing More Cells: cGMP Culture Environments for High Yield Expansion of MSCs. Biological Industries USA, Application Note.